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mrpF [2019-06-06 10:41:10]
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mrpF [2019-06-06 10:41:10]

Na+/H+ antiporter subunit, multiple resistance and pH homeostasis
locus
BSU31650
pI
8.82
mw
10.09 kDa
protein length
94 aa Sequence Blast
gene length
285 bp Sequence Blast
function
sodium export
product
Na+/H+ antiporter subunit
essential
yes
synonyms
yufC
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.5|Metal ion transporter]
  • [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.1|Metal ion homeostasis (K, Na, Ca, Mg)] → [category|SW 1.3.1.2|Sodium uptake/ export]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    3,251,724 3,252,008

    Phenotypes of a mutant

  • essential [Pubmed|12682299]

    • The protein

    Structure

  • [PDB|6CFW] (from Pyrococcus furiosus, 31% identity) [pubmed|29754813]

    • [SW|Localization]

  • cell membrane (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|E968DECF869CAF7E247A518494AD70B554A7A25F|mrpA]-[gene|AAB15E7E3E3701AA3159370B85C151994244BA5B|mrpB]-[gene|D921139B18A665E9BB177C973FCF050A4BFFF97F|mrpC]-[gene|051D9BCC0CB05E39ED5825BB9BA77B8228EA055D|mrpD]-[gene|BF233467FAF95EEEE12A0D36C543DB357D8879EA|mrpE]-[gene|5CA2EA2D60FE4696903C16698C8329A20CBEBF72|mrpF]-[gene|B28796716C7E6C924F55176453DDBF9ADD0EF755|mrpG]
    description
    [Pubmed|9274030,10198001]
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    Biological materials

    Mutant

  • MGNA-A640 (yufC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/640 NBRP B. subtilis, Japan]

    • References

    Reviews

  • 29218041

    • Original publications

  • 11004162,17693497,10198001,18408029,29754813